Since radial chromosomes have multiple centromeres, they can thwart normal chromosome segregation. Figure 4. Figure 3.
EMBO J 29 : — Escort Chanda, deletion of the OD domain, which has been implicated in synapsis in V D J recombination, also diminished the rate of telomere fusions Fig.
Escort Chanda 7. The joining of dysfunctional telomeres was the first of the three Escort Chanda c-NHEJ Escort Chanda where a striking dependency on 53BP1 was observed Dimitrova et al. In G1, deprotected telomeres behave like one-ended DSBs, analogous to a reversed replication fork in S phase.
PARP1 is required for the Escort Chanda of single-stranded breaks SSBs that result from oxidative damage and are formed during base excision repair BER Barnes and Lindahl ; Ray Chaudhuri and Nussenzweiga pathway that removes thousands Escort Chanda aberrant nucleotides per genome each day Fig. Escort Chanda Escort Chanda 70 : — Nat Cell Biol 12 : — Nat Cell Escort Chanda 19 : 1 — 9. Adv Immunol : Escort Chanda —
SSA is a dangerous repair pathway in genomes with many repetitive sequences, since deletions will be a frequent outcome.
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